|The Spider Slayers: Part 1|
|Air date||October 8, 2016|
|Written by||Paul Giacoppo|
|Directed by||Young Ki Yoon|
Strange Little Halloween
The Spider Slayers: Part 2
|“||Get into some trouble, punks?||”|
The Spider-Slayers: Part 1 is the twenty first episode of the fourth season of Ultimate Spider-Man.
- Avengers (mentioned)
- Nova/Sam Alexander (mentioned)
- Arnim Zola (mentioned)
- Curt Connors (mentioned)
- Loki (mentioned)
- Drake Bell as Spider-Man/Peter Parker and Kaine
- Tom Kenny as Doctor Octopus/Dr. Otto Octavius
- Scott Porter as Scarlet Spider/Ben Reilly and Synth-Scarlet Spiders
- Tara Strong as Spider-Woman/Mary Jane Watson
- In the beginning of the episode, Peter mentions Loki having swapped bodies with him to backstab the Avengers in The Avenging Spider-Man Part 1.
- This episode marks the return of Scarlet Spider.
- This marks the first animated appearance of Mary Jane as Spider-Woman.