Mary Jane Watson
The The Spider-Verse: Part 3, she is used as bait by the Green Goblin so that the Goblin can steal Spider-Man Noir's DNA, and points out that Spider-Man Noir shouldn't isolate people that care.
The episode Return to the Spider-Verse: Part 3 revealed that Mary Jane was killed as a result of a gang war between Joe Fixit and Hammerhead. The fight caused a building to come crashing down, and she went in to rescue some of the residents. Fixit tried to hold the building up to save Mary Jane but failed, causing Spider-Man Noir blaming Fixit for his failure.
Like her alternate counterpart, Mary Jane is very supportive of her world's version Spider-Man and wants to show that he really is a hero. She is also very brave, attempting to attack The Goblin, a creature much bigger and stronger than she is.