|First appearance:||Great Power|
The Frightful Four is a small group of supervillains that serves as an anti-hero team of the Fantastic Four.
Since then they were locked up in maximum-security prison, signaling the end of the Frightful Four. After Trapster freed them from prison, they were sent to capture Spider-Man and escaped them.
The Frightful Four invade an OsCorp warehouse and end up fighting Spider-Man's team. It soon turns out that the Frightful Four had set a trap where they escape while Spider-Man's team are attacked by Doctor Octopus's Octobots.
Spider-Man finds Iron Patriot (Norman Osborn) fighting the Frightful Four on a rooftop. During the fight with the Frightful Four, Trapster places the bombs on Iron Patriot which disables him, causing Spider-Man to resume the fight. However, this was just a strategy play by Iron Patriot to defeat the Frightful Four. Osborn was trying to make amends for the incident where they attacked Midtown High.
- The Frightful Four made an appearance with all four members present when they fight Iron Patriot and Spider-Man.
- Trapster appeared more times than the other members of the Frightful Four.